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Mouse Mutagenesis with the Chemical Supermutagen ENU

The generation and analysis of germline mutations in the mouse is one of the cornerstones of modern biological research. The chemical supermutagen N-ethyl-N-nitrosourea (ENU) is the most potent known mouse mutagen and can be used to generate point mutations throughout the mouse genome. The progeny o...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Probst, Frank J., Justice, Monica J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484834/
https://ncbi.nlm.nih.gov/pubmed/20699147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(10)77015-4
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