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High Density Lipoprotein-Mimicking Nanodiscs for Chemo-Immunotherapy against Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is an aggressive primary brain tumor, for which there is no cure. Treatment effectiveness for GBM has been limited due to tumor heterogeneity, an immunosuppressive tumor microenvironment (TME) and the presence of the blood brain barrier, which hampers the transport of c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ACS Nano
Hauptverfasser: Kadiyala, Padma, Li, Dan, Nuñez, Fernando M., Altshuler, David, Doherty, Robert, Kuai, Rui, Yu, Minzhi, Kamran, Neha, Edwards, Marta, Moon, James J., Lowenstein, Pedro R., Castro, Maria G., Schwendeman, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484828/
https://ncbi.nlm.nih.gov/pubmed/30721028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b06842
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