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Designer vaccine nanodiscs for personalized cancer immunotherapy

Despite the tremendous potential of peptide-based cancer vaccines, their efficacy has been limited in humans. Recent innovations in tumor exome sequencing have signaled the new era of personalized immunotherapy with patient-specific neo-antigens, but a general methodology for stimulating strong CD8α...

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Bibliographic Details
Published in:Nat Mater
Main Authors: Kuai, Rui, Ochyl, Lukasz J., Bahjat, Keith S., Schwendeman, Anna, Moon, James J.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374005/
https://ncbi.nlm.nih.gov/pubmed/28024156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4822
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