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Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy

Recent studies have shown that certain combinations of Toll-like receptor (TLR) agonists can induce synergistic immune activation. However, it remains challenging to achieve such robust responses in vivo in a manner that is effective, facile, and amenable for clinical translation. Here, we show that...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Kuai, Rui, Sun, Xiaoqi, Yuan, Wenmin, Ochyl, Lukasz J., Xu, Yao, Najafabadi, Alireza Hassani, Scheetz, Lindsay, Yu, Min-Zhi, Balwani, Ishina, Schwendeman, Anna, Moon, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056764/
https://ncbi.nlm.nih.gov/pubmed/29702142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.04.041
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