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Perturbations in the impact of mutational activity on Vλ genes in systemic lupus erythematosus
To assess the impact of somatic hypermutation and selective influences on the Vλ light chain repertoire in systemic lupus erythematosus (SLE), the frequency and pattern of mutations were analyzed in individual CD19(+) B cells from a patient with previously undiagnosed SLE. The mutational frequency o...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC64848/ https://ncbi.nlm.nih.gov/pubmed/11714391 |
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