Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway

p53, circRNAs and miRNAs are important components of the regulatory network that activates the EMT program in cancer metastasis. In prostate cancer (PCa), however, it has not been investigated whether and how p53 regulates EMT by circRNAs and miRNAs. Here we show that a Amotl1-derived circRNA, terme...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Yang, Zhan, Qu, Chang-Bao, Zhang, Yong, Zhang, Wen-Feng, Wang, Dan-Dan, Gao, Chun-Cheng, Ma, Long, Chen, Jin-Suo, Liu, Kai-Long, Zheng, Bin, Zhang, Xin-Hua, Zhang, Man-Li, Wang, Xiao-Lu, Wen, Jin-Kun, Li, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484770/
https://ncbi.nlm.nih.gov/pubmed/30531834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0602-8
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge