Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway

p53, circRNAs and miRNAs are important components of the regulatory network that activates the EMT program in cancer metastasis. In prostate cancer (PCa), however, it has not been investigated whether and how p53 regulates EMT by circRNAs and miRNAs. Here we show that a Amotl1-derived circRNA, terme...

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書誌詳細
出版年:Oncogene
主要な著者: Yang, Zhan, Qu, Chang-Bao, Zhang, Yong, Zhang, Wen-Feng, Wang, Dan-Dan, Gao, Chun-Cheng, Ma, Long, Chen, Jin-Suo, Liu, Kai-Long, Zheng, Bin, Zhang, Xin-Hua, Zhang, Man-Li, Wang, Xiao-Lu, Wen, Jin-Kun, Li, Wei
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484770/
https://ncbi.nlm.nih.gov/pubmed/30531834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0602-8
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