Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway

p53, circRNAs and miRNAs are important components of the regulatory network that activates the EMT program in cancer metastasis. In prostate cancer (PCa), however, it has not been investigated whether and how p53 regulates EMT by circRNAs and miRNAs. Here we show that a Amotl1-derived circRNA, terme...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Yang, Zhan, Qu, Chang-Bao, Zhang, Yong, Zhang, Wen-Feng, Wang, Dan-Dan, Gao, Chun-Cheng, Ma, Long, Chen, Jin-Suo, Liu, Kai-Long, Zheng, Bin, Zhang, Xin-Hua, Zhang, Man-Li, Wang, Xiao-Lu, Wen, Jin-Kun, Li, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484770/
https://ncbi.nlm.nih.gov/pubmed/30531834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0602-8
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