Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature

Because angiogenesis plays a major role in the perpetuation of inflammatory arthritis, we explored a method for selectively targeting and destroying new synovial blood vessels. Mice with collagen-induced arthritis were injected intravenously with phage expressing an RGD motif. In addition, the RGD p...

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Veröffentlicht in:	Arthritis Res
Hauptverfasser:	Gerlag, Danielle M, Borges, Eric, Tak, Paul P, Ellerby, H Michael, Bredesen, Dale E, Pasqualini, Renata, Ruoslahti, Erkki, Firestein, Gary S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2001
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11714389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar327
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