Naftopidil reduced the proliferation of lung fibroblasts and bleomycin‐induced lung fibrosis in mice

Naftopidil, an α‐1 adrenoceptor antagonist with few adverse effects, is prescribed for prostate hyperplasia. Naftopidil inhibits prostate fibroblast proliferation; however, its effects on lung fibroblasts and fibrosis remain largely unknown. Two normal and one idiopathic pulmonary fibrosis human lun...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Urushiyama, Hirokazu, Terasaki, Yasuhiro, Nagasaka, Shinya, Kokuho, Nariaki, Endo, Youko, Terasaki, Mika, Kunugi, Shinobu, Makita, Kosuke, Isago, Hideaki, Hosoki, Keisuke, Souma, Kunihiko, Ishii, Takashi, Matsuzaki, Hirotaka, Hiraishi, Yoshihisa, Mikami, Yu, Noguchi, Satoshi, Tamiya, Hiroyuki, Mitani, Akihisa, Yamauchi, Yasuhiro, Shimizu, Akira, Nagase, Takahide
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484423/
https://ncbi.nlm.nih.gov/pubmed/30873733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14255
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