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Inhibition of P53/miR‐34a improves diabetic endothelial dysfunction via activation of SIRT1

Endothelial dysfunction contributes to diabetic macrovascular complications, resulting in high mortality. Recent findings demonstrate a pathogenic role of P53 in endothelial dysfunction, encouraging the investigation of the effect of P53 inhibition on diabetic endothelial dysfunction. Thus, high glu...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Wu, Junduo, Liang, Wenzhao, Tian, Yueli, Ma, Fuzhe, Huang, Wenlin, Jia, Ye, Jiang, Ziping, Wu, Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484332/
https://ncbi.nlm.nih.gov/pubmed/30793480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14253
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