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The Legionella effector RavD binds phosphatidylinositol-3-phosphate and helps suppress endolysosomal maturation of the Legionella-containing vacuole

Upon phagocytosis into macrophages, the intracellular bacterial pathogen Legionella pneumophila secretes effector proteins that manipulate host cell components, enabling it to evade lysosomal degradation. However, the bacterial proteins involved in this evasion are incompletely characterized. Here w...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pike, Colleen M., Boyer-Andersen, Rebecca, Kinch, Lisa N., Caplan, Jeffrey L., Neunuebel, M. Ramona
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484141/
https://ncbi.nlm.nih.gov/pubmed/30733336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007086
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