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15-Deoxy-Δ(12,14)-prostaglandin J2 promotes phosphorylation of eukaryotic initiation factor 2α and activates the integrated stress response

Stress granules (SGs) are cytoplasmic RNA–protein aggregates formed in response to inhibition of translation initiation. SGs contribute to the stress response and are implicated in a variety of diseases, including cancer and some forms of neurodegeneration. Neurodegenerative diseases often involve c...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tauber, Devin, Parker, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484127/
https://ncbi.nlm.nih.gov/pubmed/30723157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007138
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