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15-Deoxy-Δ(12,14)-prostaglandin J2 promotes phosphorylation of eukaryotic initiation factor 2α and activates the integrated stress response

Stress granules (SGs) are cytoplasmic RNA–protein aggregates formed in response to inhibition of translation initiation. SGs contribute to the stress response and are implicated in a variety of diseases, including cancer and some forms of neurodegeneration. Neurodegenerative diseases often involve c...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Tauber, Devin, Parker, Roy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484127/
https://ncbi.nlm.nih.gov/pubmed/30723157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007138
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