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Functional reconstitution of vacuolar H(+)-ATPase from V(o) proton channel and mutant V(1)-ATPase provides insight into the mechanism of reversible disassembly

The vacuolar H(+)-ATPase (V-ATPase; V(1)V(o)-ATPase) is an ATP-dependent proton pump that acidifies subcellular compartments in all eukaryotic organisms. V-ATPase activity is regulated by reversible disassembly into autoinhibited V(1)-ATPase and V(o) proton channel subcomplexes, a process that is po...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Sharma, Stuti, Oot, Rebecca A., Khan, Md Murad, Wilkens, Stephan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484122/
https://ncbi.nlm.nih.gov/pubmed/30792311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007577
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