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Functional reconstitution of vacuolar H(+)-ATPase from V(o) proton channel and mutant V(1)-ATPase provides insight into the mechanism of reversible disassembly
The vacuolar H(+)-ATPase (V-ATPase; V(1)V(o)-ATPase) is an ATP-dependent proton pump that acidifies subcellular compartments in all eukaryotic organisms. V-ATPase activity is regulated by reversible disassembly into autoinhibited V(1)-ATPase and V(o) proton channel subcomplexes, a process that is po...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484122/ https://ncbi.nlm.nih.gov/pubmed/30792311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007577 |
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