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Sensory primary cilium is a responsive cAMP microdomain in renal epithelia

Primary cilia are hair-like cellular extensions that sense microenvironmental signals surrounding cells. The role of adenylyl cyclases in ciliary function has been of interest because the product of adenylyl cyclase activity, cAMP, is relevant to cilia-related diseases. In the present study, we show...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Sherpa, Rinzhin T., Mohieldin, Ashraf M., Pala, Rajasekharreddy, Wachten, Dagmar, Ostrom, Rennolds S., Nauli, Surya M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484033/
https://ncbi.nlm.nih.gov/pubmed/31024067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43002-2
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