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Sensory primary cilium is a responsive cAMP microdomain in renal epithelia

Primary cilia are hair-like cellular extensions that sense microenvironmental signals surrounding cells. The role of adenylyl cyclases in ciliary function has been of interest because the product of adenylyl cyclase activity, cAMP, is relevant to cilia-related diseases. In the present study, we show...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Sherpa, Rinzhin T., Mohieldin, Ashraf M., Pala, Rajasekharreddy, Wachten, Dagmar, Ostrom, Rennolds S., Nauli, Surya M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484033/
https://ncbi.nlm.nih.gov/pubmed/31024067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43002-2
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