Placebo response and remission rates in randomised trials of induction and maintenance therapy for ulcerative colitis

BACKGROUND: It is important to minimize placebo rates in randomised controlled trials (RCTs) to efficiently detect treatment differences between interventions. Historically, high placebo rates have been observed in clinical trials of ulcerative colitis (UC). A better understanding of factors influen...

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Detalhes bibliográficos
Publicado no:Cochrane Database Syst Rev
Main Authors: Jairath, Vipul, Zou, GY, Parker, Claire E, MacDonald, John K, AlAmeel, Turki, Al Beshir, Mohammad, Almadi, Majid A, Al‐Taweel, Talal, Atkinson, Nathan SS, Biswas, Sujata, Chapman, Thomas, Dulai, Parambir S, Glaire, Mark A, Hoekman, Daniël R, Koutsoumpas, Andreas, Minas, Elizabeth, Mosli, Mahmoud H, Samaan, Mark, Khanna, Reena, Travis, Simon, D'Haens, Geert, Sandborn, William J, Feagan, Brian G
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483671/
https://ncbi.nlm.nih.gov/pubmed/28886205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD011572.pub2
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