Systematic Review and Meta-analysis: Placebo Rates in Induction and Maintenance Trials of Ulcerative Colitis

BACKGROUND AND AIMS: Minimisation of the placebo responses in randomised controlled trials [RCTs] is essential for efficient evaluation of new interventions. Placebo rates have been high in ulcerative colitis [UC] clinical trials, and factors influencing this are poorly understood. We quantify place...

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Veröffentlicht in:J Crohns Colitis
Hauptverfasser: Jairath, Vipul, Zou, Guangyong, Parker, Claire E., Macdonald, John K., Mosli, Mahmoud H., Khanna, Reena, Shackelton, Lisa M., Vandervoort, Margaret K., AlAmeel, Turki, Al Beshir, Mohammad, AlMadi, Majid, Al-Taweel, Talal, Atkinson, Nathan S. S., Biswas, Sujata, Chapman, Thomas P., Dulai, Parambir S., Glaire, Mark A., Hoekman, Daniel, Koutsoumpas, Andreas, Minas, Elizabeth, Samaan, Mark A., Travis, Simon, D’Haens, Geert, Levesque, Barrett G., Sandborn, William J., Feagan, Brian G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957452/
https://ncbi.nlm.nih.gov/pubmed/26746169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjw004
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