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TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons
The satiety effects and metabolic actions of cholecystokinin (CCK) have been recognized as potential therapeutic targets in obesity for decades. We identified a potentially novel Ca(2+)-activated chloride (Cl(–)) current (CaCC) that is induced by CCK in intestinal vagal afferents of nodose neurons....
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483506/ https://ncbi.nlm.nih.gov/pubmed/30843875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122058 |
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