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TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons
The satiety effects and metabolic actions of cholecystokinin (CCK) have been recognized as potential therapeutic targets in obesity for decades. We identified a potentially novel Ca(2+)-activated chloride (Cl(–)) current (CaCC) that is induced by CCK in intestinal vagal afferents of nodose neurons....
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| Published in: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483506/ https://ncbi.nlm.nih.gov/pubmed/30843875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122058 |
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