Nanoparticle-Encapsulated Doxorubicin Demonstrates Superior Tumor Cell Kill in Triple Negative Breast Cancer Subtypes Intrinsically Resistant to Doxorubicin

The effect of size and release kinetics of doxorubicin-nanoparticles on anti-tumor efficacy was evaluated in a panel of human cancer cell lines, including triple-negative breast cancer (TNBC) cells that frequently demonstrate resistance to doxorubicin. Different nano-formulations of sol-gel-based Do...

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Bibliographic Details
Published in:Precis Nanomed
Main Authors: Krausz, Aimee E., Adler, Brandon L., Makdisi, Joy, Schairer, David, Rosen, Jamie, Landriscina, Angelo, Navati, Mahantesh, Alfieri, Alan, Friedman, Joel M., Nosanchuk, Joshua D., Rodriguez-Gabin, Alicia, Ye, Kenny Q, McDaid, Hayley M., Friedman, Adam J.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483385/
https://ncbi.nlm.nih.gov/pubmed/31032494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33218/prnano1(3).181029.1
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