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Disease Pathway Cut for Multi-Target drugs

BACKGROUND: Biomarker discovery studies have been moving the focus from a single target gene to a set of target genes. However, the number of target genes in a drug should be minimum to avoid drug side-effect or toxicity. But still, the set of target genes should effectively block all possible paths...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Bang, Sunjoo, Son, Sangjoon, Kim, Sooyoung, Shin, Hyunjung
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483058/
https://ncbi.nlm.nih.gov/pubmed/30760209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2638-3
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