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Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development

Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or thalassemia. The GATA1 transcription factor is an established mediator of RBC development. However, the upstream mechanisms that regulate the expression of GATA1 are not com...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Hernandez, Jose A., Castro, Victoria L., Reyes-Nava, Nayeli, Montes, Laura P., Quintana, Anita M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482358/
https://ncbi.nlm.nih.gov/pubmed/30987969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018024539
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