Frequent STAT3 mutations in CD8(+) T cells from patients with pure red cell aplasia

Dysregulation of T-cell–mediated immunity is responsible for acquired pure red cell aplasia (PRCA). Although STAT3 mutations are frequently detected in patients with T-cell large granular lymphocytic leukemia (T-LGLL), which is often complicated by PRCA and which is also reported to be associated wi...

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Veröffentlicht in:Blood Adv
Hauptverfasser: Kawakami, Toru, Sekiguchi, Nodoka, Kobayashi, Jun, Imi, Tatsuya, Matsuda, Kazuyuki, Yamane, Taku, Nishina, Sayaka, Senoo, Yasushi, Sakai, Hitoshi, Ito, Toshiro, Koizumi, Tomonobu, Hirokawa, Makoto, Nakao, Shinji, Nakazawa, Hideyuki, Ishida, Fumihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2018
Schlagworte:
Red Cells, Iron, and Erythropoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199660/
https://ncbi.nlm.nih.gov/pubmed/30337298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018022723
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