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Enantioselective Palladium-Catalyzed Oxidative β,β-Fluoroarylation of α,β-Unsaturated Carbonyl Derivatives

The site-selective palladium-catalyzed three-component coupling of deactivated alkenes, arylboronic acids and N-fluorobenzenesulfonimide is disclosed herein. The developed methodology establishes a general, modular and step-economical approach to the stereoselective β-fluorination of α,β-unsaturated...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Miró, Javier, del Pozo, Carlos, Toste, F. Dean, Fustero, Santos
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482284/
https://ncbi.nlm.nih.gov/pubmed/27272390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603046
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