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Elevation of O-GlcNAc and GFAT expression by nicotine exposure promotes epithelial‐mesenchymal transition and invasion in breast cancer cells

Cigarette smoking has been shown to be a carcinogenic factor in breast cancer. Nicotine (Nic), an active component of tobacco, has been found to induce epithelial-mesenchymal transition (EMT) in breast cancer cells. However, the alterations in protein O-GlcNAcylation in Nic-mediated tumorigenesis an...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Nana, Zhu, Tong, Yu, Kairan, Shi, Meiyun, Wang, Xue, Wang, Lingyan, Huang, Tianmiao, Li, Wenli, Liu, Yubo, Zhang, Jianing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482138/
https://ncbi.nlm.nih.gov/pubmed/31019204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1577-2
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