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In vivo synaptic activity-independent co-uptakes of amyloid β(1–42) and Zn(2+) into dentate granule cells in the normal brain
Neuronal amyloid β(1–42) (Aβ(1–42)) accumulation is considered an upstream event in Alzheimer’s disease pathogenesis. Here we report the mechanism on synaptic activity-independent Aβ(1–42) uptake in vivo. When Aβ(1–42) uptake was compared in hippocampal slices after incubating with Aβ(1–42), In vitr...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482136/ https://ncbi.nlm.nih.gov/pubmed/31019269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43012-0 |
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