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[(18)F]FE-OTS964: a Small Molecule Targeting TOPK for In Vivo PET Imaging in a Glioblastoma Xenograft Model

PURPOSE: Lymphokine-activated killer T-cell-originated protein kinase (TOPK) is a fairly new cancer biomarker with great potential for clinical applications. The labeling of a TOPK inhibitor with F-18 can be exploited for positron emission tomography (PET) imaging allowing more accurate patient iden...

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Publicat a:Mol Imaging Biol
Autors principals: Pirovano, Giacomo, Roberts, Sheryl, Brand, Christian, Donabedian, Patrick L., Mason, Christian, de Souza, Paula Demétrio, Higgins, Geoff S., Reiner, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482100/
https://ncbi.nlm.nih.gov/pubmed/30357568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-018-1288-6
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