Učitavanje...
Lysosomal acid lipase in lipid metabolism and beyond
Lysosomal acid lipase (LAL), encoded by the LIPA gene, hydrolyzes cholesteryl esters and triglycerides to generate free fatty acids and cholesterol in the cell. The essential role of LAL in lipid metabolism has been confirmed in mice and human with LAL deficiency. In humans, loss-of-function mutatio...
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| Izdano u: | Arterioscler Thromb Vasc Biol |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482091/ https://ncbi.nlm.nih.gov/pubmed/30866656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312136 |
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