Cortical Column and Whole Brain Imaging with Molecular Contrast and Nanoscale Resolution

Optical and electron microscopy have made tremendous inroads in understanding the complexity of the brain. However, optical microscopy offer insufficient resolution to reveal subcellular details and electron microscopy lacks the throughput and molecular contrast to visualize specific molecular const...

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Publicado en:Science
Main Authors: Gao, Ruixuan, Asano, Shoh M., Upadhyayula, Srigokul, Pisarev, Igor, Milkie, Daniel E., Liu, Tsung-Li, Singh, Ved, Graves, Austin, Huynh, Grace H., Zhao, Yongxin, Bogovic, John, Colonell, Jennifer, Ott, Carolyn M., Zugates, Christopher, Tappan, Susan, Rodriguez, Alfredo, Mosaliganti, Kishore R., Sheu, Shu-Hsien, Pasolli, H. Amalia, Pang, Song, Xu, C. Shan, Megason, Sean G., Hess, Harald, Lippincott-Schwartz, Jennifer, Hantman, Adam, Rubin, Gerald M., Kirchhausen, Tom, Saalfeld, Stephan, Aso, Yoshinori, Boyden, Edward S., Betzig, Eric
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481610/
https://ncbi.nlm.nih.gov/pubmed/30655415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau8302
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