The transcriptomic response to irinotecan in colon carcinoma bearing mice preconditioned by fasting

BACKGROUND: Irinotecan use is limited due to severe toxicity. Preconditioning by fasting (PBF) protects against side effects of irinotecan while preserving its antitumor activity. The mechanisms underlying the effects of PBF still need to be elucidated. Here, we investigated the transcriptional resp...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Jongbloed, Franny, Huisman, Sander A., van Steeg, Harry, Pennings, Jeroen L.A., IJzermans, Jan N.M., Dollé, Martijn E.T., de Bruin, Ron W.F.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2019
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481335/
https://ncbi.nlm.nih.gov/pubmed/31040913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26776
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