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The transcriptomic response to irinotecan in colon carcinoma bearing mice preconditioned by fasting

BACKGROUND: Irinotecan use is limited due to severe toxicity. Preconditioning by fasting (PBF) protects against side effects of irinotecan while preserving its antitumor activity. The mechanisms underlying the effects of PBF still need to be elucidated. Here, we investigated the transcriptional resp...

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Publicat a:Oncotarget
Autors principals: Jongbloed, Franny, Huisman, Sander A., van Steeg, Harry, Pennings, Jeroen L.A., IJzermans, Jan N.M., Dollé, Martijn E.T., de Bruin, Ron W.F.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481335/
https://ncbi.nlm.nih.gov/pubmed/31040913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26776
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