The transcriptomic response to irinotecan in colon carcinoma bearing mice preconditioned by fasting

BACKGROUND: Irinotecan use is limited due to severe toxicity. Preconditioning by fasting (PBF) protects against side effects of irinotecan while preserving its antitumor activity. The mechanisms underlying the effects of PBF still need to be elucidated. Here, we investigated the transcriptional resp...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jongbloed, Franny, Huisman, Sander A., van Steeg, Harry, Pennings, Jeroen L.A., IJzermans, Jan N.M., Dollé, Martijn E.T., de Bruin, Ron W.F.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481335/
https://ncbi.nlm.nih.gov/pubmed/31040913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26776
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