Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler’s Murine Encephalomyelitis

Theiler’s murine encephalomyelitis (TME) represents a versatile animal model for studying the pathogenesis of demyelinating diseases such as multiple sclerosis. Hallmarks of TME are demyelination, astrogliosis, as well as inflammation. Previous studies showed that matrix metalloproteinase 12 knockou...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Hansmann, Florian, Zhang, Ning, Herder, Vanessa, Leitzen, Eva, Baumgärtner, Wolfgang
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480673/
https://ncbi.nlm.nih.gov/pubmed/30959793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071702
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