Efficient gene transfer into T lymphocytes by fiber-modified human adenovirus 5

BACKGROUND: The gene transduction efficiency of adenovirus to hematopoietic cells, especially T lymphocytes, is needed to be improved. The purpose of this study is to improve the transduction efficiency of T lymphocytes by using fiber-modified human adenovirus 5 (HAdV-5) vectors. RESULTS: Four fiber...

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Veröffentlicht in:BMC Biotechnol
Hauptverfasser: Lv, Yun, Xiao, Feng-Jun, Wang, Yi, Zou, Xiao-Hui, Wang, Hua, Wang, Hai-Yan, Wang, Li-Sheng, Lu, Zhuo-Zhuang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480437/
https://ncbi.nlm.nih.gov/pubmed/31014302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-019-0514-x
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