Intracellular Delivery of Biologically-Active Fungal Metabolite Gliotoxin Using Magnetic Nanoparticles

Gliotoxin (GT), a secondary metabolite produced by Aspergillus molds, has been proposed as a potential anti-tumor agent. Here we have developed a nanoparticle approach to enhance delivery of GT in tumor cells and establish a basis for its potential use as therapeutical drug. GT bound to magnetic nan...

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Detalhes bibliográficos
Publicado no:Materials (Basel)
Main Authors: Comas, Laura, Polo, Esther, Domingo, M Pilar, Hernández, Yulán, Arias, Maykel, Esteban, Patricia, Martínez-Lostao, Luis, Pardo, Julián, Martínez de la Fuente, Jesús, Gálvez, Eva M
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480141/
https://ncbi.nlm.nih.gov/pubmed/30987007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma12071092
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