Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis

Gliotoxin (GT) is a fungal secondary metabolite that has attracted great interest due to its high biological activity since it was discovered by the 1930s. An inactive derivative of this molecule, bis(methylthio)gliotoxin (bmGT), has been proposed as an invasive aspergillosis (IA) biomarker. Neverth...

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發表在:Front Microbiol
Main Authors: Vidal-García, Matxalen, Redrado, Sergio, Domingo, M. Pilar, Marquina, Patricia, Colmenarejo, Cristina, Meis, Jacques F., Rezusta, Antonio, Pardo, Julian, Galvez, Eva M.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Microbiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006755/
https://ncbi.nlm.nih.gov/pubmed/29946309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01246
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