Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis

Gliotoxin (GT) is a fungal secondary metabolite that has attracted great interest due to its high biological activity since it was discovered by the 1930s. An inactive derivative of this molecule, bis(methylthio)gliotoxin (bmGT), has been proposed as an invasive aspergillosis (IA) biomarker. Neverth...

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Bibliografische gegevens
Gepubliceerd in:Front Microbiol
Hoofdauteurs: Vidal-García, Matxalen, Redrado, Sergio, Domingo, M. Pilar, Marquina, Patricia, Colmenarejo, Cristina, Meis, Jacques F., Rezusta, Antonio, Pardo, Julian, Galvez, Eva M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006755/
https://ncbi.nlm.nih.gov/pubmed/29946309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01246
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