Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis

Gliotoxin (GT) is a fungal secondary metabolite that has attracted great interest due to its high biological activity since it was discovered by the 1930s. An inactive derivative of this molecule, bis(methylthio)gliotoxin (bmGT), has been proposed as an invasive aspergillosis (IA) biomarker. Neverth...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Vidal-García, Matxalen, Redrado, Sergio, Domingo, M. Pilar, Marquina, Patricia, Colmenarejo, Cristina, Meis, Jacques F., Rezusta, Antonio, Pardo, Julian, Galvez, Eva M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006755/
https://ncbi.nlm.nih.gov/pubmed/29946309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01246
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