Production of the Invasive Aspergillosis Biomarker Bis(methylthio)gliotoxin Within the Genus Aspergillus: In Vitro and in Vivo Metabolite Quantification and Genomic Analysis

Gliotoxin (GT) is a fungal secondary metabolite that has attracted great interest due to its high biological activity since it was discovered by the 1930s. An inactive derivative of this molecule, bis(methylthio)gliotoxin (bmGT), has been proposed as an invasive aspergillosis (IA) biomarker. Neverth...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Vidal-García, Matxalen, Redrado, Sergio, Domingo, M. Pilar, Marquina, Patricia, Colmenarejo, Cristina, Meis, Jacques F., Rezusta, Antonio, Pardo, Julian, Galvez, Eva M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006755/
https://ncbi.nlm.nih.gov/pubmed/29946309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01246
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