PD-L1 Expression in Systemic Immune Cell Populations as a Potential Predictive Biomarker of Responses to PD-L1/PD-1 Blockade Therapy in Lung Cancer

PD-L1 tumor expression is a widely used biomarker for patient stratification in PD-L1/PD-1 blockade anticancer therapies, particularly for lung cancer. However, the reliability of this marker is still under debate. Moreover, PD-L1 is widely expressed by many immune cell types, and little is known on...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bocanegra, Ana, Fernandez-Hinojal, Gonzalo, Zuazo-Ibarra, Miren, Arasanz, Hugo, Garcia-Granda, Maria Jesus, Hernandez, Carlos, Ibañez, Maria, Hernandez-Marin, Berta, Martinez-Aguillo, Maite, Lecumberri, Maria Jose, Fernandez de Lascoiti, Angela, Teijeira, Lucia, Morilla, Idoia, Vera, Ruth, Escors, David, Kochan, Grazyna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479779/
https://ncbi.nlm.nih.gov/pubmed/30986912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071631
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