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A Molecular Dynamics Approach to Explore the Intramolecular Signal Transduction of PPAR-α
Dynamics and functions of the peroxisome proliferator-activated receptor (PPAR)-α are modulated by the types of ligands that bind to the orthosteric sites. While several X-ray crystal structures of PPAR-α have been determined in their agonist-bound forms, detailed structural information in their apo...
Enregistré dans:
| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6479491/ https://ncbi.nlm.nih.gov/pubmed/30987171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071666 |
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