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Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization
AIM: Discovery of novel series of colchicine binding site inhibitors (CBSIs). MATERIALS & METHODS: Isoxazoline 3a–d, pyrazoline 4a–b, 7a–f and 8a–f, cyclohexenone 9a–b and 10a–b or pyridine derivatives 11a–b were synthesized and evaluated for their inhibition of tubulin polymerization and cytoto...
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| Yayımlandı: | Future Med Chem |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Future Science Ltd
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6479276/ https://ncbi.nlm.nih.gov/pubmed/29966433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0036 |
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