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The combination of neoantigen quality and T lymphocyte infiltrates identifies glioblastomas with the longest survival
Glioblastoma (GBM) is resistant to multimodality therapeutic approaches. A high burden of tumor-specific mutant peptides (neoantigens) correlates with better survival and response to immunotherapies in selected solid tumors but how neoantigens impact clinical outcome in GBM remains unclear. Here, we...
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| Pubblicato in: | Commun Biol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478916/ https://ncbi.nlm.nih.gov/pubmed/31044160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0369-7 |
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