The combination of neoantigen quality and T lymphocyte infiltrates identifies glioblastomas with the longest survival

Glioblastoma (GBM) is resistant to multimodality therapeutic approaches. A high burden of tumor-specific mutant peptides (neoantigens) correlates with better survival and response to immunotherapies in selected solid tumors but how neoantigens impact clinical outcome in GBM remains unclear. Here, we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Commun Biol
Egile Nagusiak: Zhang, Jing, Caruso, Francesca P., Sa, Jason K., Justesen, Sune, Nam, Do-Hyun, Sims, Peter, Ceccarelli, Michele, Lasorella, Anna, Iavarone, Antonio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478916/
https://ncbi.nlm.nih.gov/pubmed/31044160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0369-7
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