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A 3.8 Å resolution cryo-EM structure of a small protein bound to an imaging scaffold

Proteins smaller than about 50 kDa are currently too small to be imaged at high resolution by cryo-electron microscopy (cryo-EM), leaving most protein molecules in the cell beyond the reach of this powerful structural technique. Here we use a designed protein scaffold to bind and symmetrically displ...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Liu, Yuxi, Huynh, Duc T., Yeates, Todd O.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478846/
https://ncbi.nlm.nih.gov/pubmed/31015551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09836-0
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