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SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles
Primordial follicles, consisting of granulosa cell (GC)-enveloped oocytes are maintained in a state of developmental arrest until activated to grow. The mechanism that operates to maintain this arrested state in GCs is currently unknown. Here, we show the TGFβ-activated transcription factor SMAD3 is...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478827/ https://ncbi.nlm.nih.gov/pubmed/31015579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42878-4 |
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