Targeting T Cell Activation and Lupus Autoimmune Phenotypes by Inhibiting Glucose Transporters

CD4(+) T cells have numerous features of over-activated cellular metabolism in lupus patients and mouse models of the disease. This includes a higher glycolysis than in healthy controls. Glucose transporters play an essential role in glucose metabolism by controlling glucose import into the cell fro...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Li, Wei, Qu, Ganlin, Choi, Seung-Chul, Cornaby, Caleb, Titov, Anton, Kanda, Natalie, Teng, Xiangyu, Wang, Haiting, Morel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478810/
https://ncbi.nlm.nih.gov/pubmed/31057554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00833
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