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Targeting T Cell Activation and Lupus Autoimmune Phenotypes by Inhibiting Glucose Transporters
CD4(+) T cells have numerous features of over-activated cellular metabolism in lupus patients and mouse models of the disease. This includes a higher glycolysis than in healthy controls. Glucose transporters play an essential role in glucose metabolism by controlling glucose import into the cell fro...
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| Publicat a: | Front Immunol |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478810/ https://ncbi.nlm.nih.gov/pubmed/31057554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00833 |
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