Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling

Sanguinarine (SNG), a benzophenanthridine alkaloid, has displayed various anticancer abilities in several vivo and in vitro studies. However, the anticancer potential of SNG is yet to be established in multiple myeloma (MM), a mostly incurable malignancy of plasma cells. In this study, we aimed to i...

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Vydáno v:Front Oncol
Hlavní autoři: Akhtar, Sabah, Achkar, Iman W., Siveen, Kodappully S., Kuttikrishnan, Shilpa, Prabhu, Kirti S., Khan, Abdul Q., Ahmed, Eiman I., Sahir, Fairooz, Jerobin, Jayakumar, Raza, Afsheen, Merhi, Maysaloun, Elsabah, Hesham M., Taha, Ruba, Omri, Halima El, Zayed, Hatem, Dermime, Said, Steinhoff, Martin, Uddin, Shahab
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478801/
https://ncbi.nlm.nih.gov/pubmed/31058086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00285
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