Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli

The bacterial cell wall plays a crucial role in viability and is an important drug target. In Escherichia coli, the peptidoglycan crosslinking reaction to form the cell wall is primarily carried out by penicillin-binding proteins that catalyse D,D-transpeptidase activity. However, an alternate cross...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Caveney, Nathanael A., Caballero, Guillermo, Voedts, Henri, Niciforovic, Ana, Worrall, Liam J., Vuckovic, Marija, Fonvielle, Matthieu, Hugonnet, Jean-Emmanuel, Arthur, Michel, Strynadka, Natalie C. J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478713/
https://ncbi.nlm.nih.gov/pubmed/31015395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09507-0
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