Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections

The bacterial cell wall plays a key role in viability and is an important drug target. The cell wall is made of elongated polymers that are cross-linked to one another to form a load-bearing mesh. An alternative cell wall cross-linking mechanism used by the l,d-transpeptidase YcbB has been implicate...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Caveney, N. A., Serapio-Palacios, A., Woodward, S. E., Bozorgmehr, T., Caballero, G., Vuckovic, M., Deng, W., Finlay, B. B., Strynadka, N. C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849009/
https://ncbi.nlm.nih.gov/pubmed/33139287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01592-20
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