Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data

BACKGROUND: Colorectal cancer (CRC) is one of the main causes of cancer-related deaths in China and around the world. Advanced CRC (ACRC) patients suffer from a low cure rate though treated with targeted therapies. The response rate is about 50% to chemotherapy and cetuximab, a monoclonal antibody t...

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Vydáno v:World J Gastroenterol
Hlavní autoři: Guo, Gui-Fang, Wang, Yi-Xing, Zhang, Yi-Jun, Chen, Xiu-Xing, Lu, Jia-Bin, Wang, Hao-Hua, Jiang, Chang, Qiu, Hui-Quan, Xia, Liang-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2019
Témata:
Basic Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478617/
https://ncbi.nlm.nih.gov/pubmed/31057298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i15.1840
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