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Predicting cetuximab accumulation in KRAS wild‐type and KRAS mutant colorectal cancer using (64)Cu‐labeled cetuximab positron emission tomography

Overexpression of epidermal growth factor receptor (EGFR) is common in colorectal cancer. However, cetuximab as an EGFR‐targeting drug is useful only for a subset of patients and currently no single predictor other than V‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation status has...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Achmad, Arifudin, Hanaoka, Hirofumi, Yoshioka, Hiroki, Yamamoto, Shinji, Tominaga, Hideyuki, Araki, Takuya, Ohshima, Yasuhiro, Oriuchi, Noboru, Endo, Keigo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713619/
https://ncbi.nlm.nih.gov/pubmed/22126621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2011.02166.x
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