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Negligible role for deletion mediated by cDC1 in CD8(+) T cell tolerance
Deletion of CD8(+) T cells by dendritic cells (DCs) is recognized as a critical mechanism of immune tolerance to self-antigens. Although DC-mediated peripheral deletion of autoreactive CD8(+) T cells has been demonstrated using T cells reactive to model antigens, its role in shaping the naturally-oc...
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| Publicado en: | J Immunol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478510/ https://ncbi.nlm.nih.gov/pubmed/30902900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801621 |
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